up
adj: Happily excited; euphoric: After receiving the award, the performer was really up.
n: A feeling of excitement or euphoria.

upchuck
tr. & intr.v. upchucked, upchucking, upchucks
To vomit or experience vomiting.

upper n:
1. A drug, especially an amphetamine, used as a stimulant.
2. An exhilarating or euphoric experience.

uptight adj:
1. Tense; nervous.
2. Financially pressed; destitute.
3. Outraged; angry.
4. Rigidly conventional, as in manners, opinions, and tastes.
uptightness n.